IOTA Pharmaceuticals

Email Usinfo@iotapharma.com

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IOTA Pharmaceuticals

 
Fragment - based Drug Discovery
Neglected Parasitic Disease
Glioma & Glioblastoma
 
 
IOTA Pharmaceuticals

IOTA currently offers a unique "Diverse 1500" fragment Library, in a number of formats, dispatched as pre-weighed, dry powders in individually sealed tubes

IOTA's "Micro Library" format is ideal for 96-well biochemical screening applications, containing 1500 x 1 mg of each fragment;
IOTA's "Standard Library" format is best for hit profiling, containing 80 x 10 mg of each fragment;
IOTA's "Mega Library" format is best for hit expansion, containing 50 mg of each selected fragment.
 
IOTA Libraries
IOTA “Diverse 1500” - Micro Library format 30 x 50 diverse fragments, 1 mg of each [1] Contact
IOTA “Diverse 1500” - Standard Library format 80 fragments selected from IOTA's Diverse 1500 Library, 10 mg of each [2] Contact
IOTA “Diverse 1500” - Mega Library format Single fragments selected from IOTA's Diverse 1500 Library, 50 mg of each [3] Contact
 
Notes
1. Fragments in IOTA's “Diverse 1500” Library have been specifically synthesised to cover “diverse” chemical space. The majority of these fragments are unique to IOTA – they cannot be purchased elsewhere. Most of the fragments are soluble at 1mM, obeying the Astex “Rule of 3”.
   
2. Individual fragments from IOTA’s “Diverse 1500” Library can be purchased in 80 fragment “sets”. Selection of the fragments within each set can either be made by computational chemistry screening of the “Diverse 1500” Library against your target of choice under confidentiality, or selected by performing a complete biochemical screen of the “Diverse 1500” against your target of choice, followed by “hit” purchase. IOTA can ship appropriate quantities of the “Diverse 1500” library to your labs for screening, or we can run your screen in IOTA’s labs under your scientist's direction – it's your choice.
   
3. Single fragments (50mg) can be purchased from IOTA upon inspection of the chemical structures within the “Diverse 1500” library under confidentiality
   

Contact IOTA’s Business Development team at info@iotapharma.com to discuss Options 2 and 3 in more detail.

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